Parathyroid hormone-related peptide stimulates intestinal strontium absorption in Camels (Camelus dromedarius)
نویسندگان
چکیده
The present work was undertaken to evaluate the stimulatory effect of Parathyroid hormone-related peptide (PTHrP) on the intestinal calcium (Ca) absorption using stable strontium (Sr) as a surgoate marker in 10 Camels. The animals were randomly divided into two groups of five animals. Just after an oral Sr load (4.1 mmol of SrCl2), the first and the second (control) groups received either an i.v infusion of synthetic human PTHrP or solvent alone respectively. PTHrP induced a significant rise in levels of plasma Sr (52.8 ± 4.6 μmol/L VS 41.7 ± 4.5 μmol/L, P < 0.05, at the second hour after oral Sr load) and urinay Pi excretion comparatively with animal controls. Plasma Sr levels remained very higher in treated animals than those measured in controls until the fifth hour of experimentation (52 ± 4.7 μmol/L VS 42.1 ± 4.5 μmol/L, P < 0.05). PTHrP did not induce significant variation on Ca or Sr renal excretion. Our results seem to show that PTHrP may play an important role on modulation of intestinal Ca absorption in camels.
منابع مشابه
Parathyroid Hormone-Related Peptide and Vitamin D in Phosphocalcic Metabolism for Dromedary Camel
In mammals, phosphocalcic and bone metabolisms are mainly regulated by parathyroid hormone, parathyroid hormone-related peptide (PTHrP) and 1α,25-dihydroxyvitamin D or calcitriol. In camels, circulating levels of calcitriol are 10 times higher than those determined in other ruminants and further increase during early lactation. Calcitriol and parathyroid-related peptide stimulate intestinal abs...
متن کاملIsolation and molecular characterization of partial FSH and LH receptor genes in Arabian camels (Camelus dromedarius)
Very little is known about LHR and FSHR genes of domestic dromedary camels. The main objective of this study was to determine and analyze partial genomic regions of FSHR and LHR genes in dromedary camels for the first time. To this end, a total of50 DNA samples belonging to dromedary camels raised in Iran were sent for sequencing (25 samples of each gene). We compared the nucleotide sequences o...
متن کاملIsolation and molecular characterization of partial FSH and LH receptor genes in Arabian camels (Camelus dromedarius)
Very little is known about LHR and FSHR genes of domestic dromedary camels. The main objective of this study was to determine and analyze partial genomic regions of FSHR and LHR genes in dromedary camels for the first time. To this end, a total of 50 DNA samples belonging to dromedary camels raised in Iran were sent for sequencing (25 samples of each gene). We compared the nucleotide sequences ...
متن کاملGastrointestinal parasites infection in one-humped camels (Camelus dromedarius) of Nigeria
One hundred and five (105) Camels were investigated at the Maiduguri abattoir, Nigeria using floatation and sedimentation techniques for helminth parasites and haematological indices with the microhaematocrit reader. Overall, prevalence of infection was 92.4% [(Coccidia (8.5%), Strongyloides (8.5%), Trichuris (11.4%), Ciliates (6.7%), Ascaris sp. (3.8%), Moniezia sp. (1.9%), Amphistome sp. (0.9...
متن کامل